Rowland Elwell
Executive Medical Director, Nephrology Calliditas
Seminars
Wednesday 19th August 2026
Targeting the Cause or the Consequence: Drug Development Strategies Across the Disease Cascade in IgA Nephropathy
11:40 am
- Exploring IgA nephropathy pathophysiology and the “four-hit” cascade to differentiate upstream causes versus downstream disease consequences
- Comparing therapeutic strategies targeting mucosal immune drivers versus kidneylevel effects, highlighting emerging approaches across the disease cascade
- Demonstrating how early intervention at disease origin impacts biomarkers, proteinuria, and kidney function, alongside evolving endpoints and clinical data
