William Smoyer

Company: Nationwide Children's Hospital

Job title: Vice President - Clinical & Translational Research

Seminars:

Applying Systems Biology Approaches to Identify Injury Mechanisms & Glomerular Extracellular Matrix (ECM) Modulation as a Potential Therapeutic Approach for Proteinuria Reduction in Idiopathic Nephrotic Syndrome 10:00 am

Isolating glomerular tissue to enable discovery-based studies to identify potential therapeutic targets for glomerular disease Analyzing rat glomerular transcriptomic data to understand molecular pathway dysregulation and cell types affected Recognizing amelioration of dysregulated glomerular ECM dynamics as a potentially targetable pathway for proteinuria reduction in idiopathic nephrotic syndromeRead more

day: Conference Day One

Reaching, Enrolling, & Retaining Participants in Rare Disease Clinical Trials 8:31 am

Dissecting real-world examples to prepare for the length and ambition of studies Evolving strategies to identify patients for rare disease clinical trials: Using electronic health records (EHRs) to identify computable phenotypes and conduct life-course research Discussing friction points and strategy for pharmacological interventions, as well as combination trials alongside preexisting patient care, and gene therapies…Read more

day: Workshop D