Nikhil Agrawal

Company: AstraZeneca

Job title: Global Development Medical Director

Seminars:

3:00 PM Delving into Clinical Trial Design for APOL1-Mediated Kidney Disease 3:00 pm

Updates on the progression of the AZD2373 for the treatment of APOL1-Mediated kidney disease Delving into successful phase 2 study design in rare renal diseases Unpacking the mechanism of action for mineralocorticoid receptor agonists Read more

day: Conference Day 1

3:30 PM Panel Discussion: Lessons Learnt from Successful Clinical Trials in IgAN & C3G to Inform Successful Clinical Design & Development in Wider Rare & Genetic Kidney Diseases 3:30 pm

Advancing understanding of disease pathophysiology and biomarker identification to guide the development of therapies with distinguished mechanism of actions Discussing suitable design of placebo arm and standard of care for rare diseases Examining the importance of integrating patient-reported outcomes, quality of like measures and comparative effectiveness research early in clinical development to demonstrate meaningful differentiationRead more

day: Conference Day 1

5:00 PM Panel: Discussing the Evolving Role of Biomarkers for Therapeutic Differentiation in a Crowded Landscape 5:00 pm

Exploring the increasing need for biomarkers that can meaningfully differentiate the clinical impact of emerging renal therapies for rare kidney diseases Discussing the repurposing of established biomarkers in new contexts to reveal subtle and clinically relevant differences between new treatments Addressing opportunities and challenges in utilizing novel biomarkers in rare kidney disease trials to demonstrate…Read more

day: Conference Day 1