Kidney Biopsy Profiling: Revealing Drug Mechanisms & Responsive Patient Subgroups in Kidney Disease Trials

• Profiling patient kidney tissue before and during clinical trials to understand molecular changes and identify early signals of therapeutic response
• Comparing trial biopsy data with longitudinal cohort datasets to determine where drugs succeed or fail mechanistically
• Advancing precision medicine by linking molecular tissue changes with clinical outcomes and guiding future biomarker-driven trial design

Speakers:

Sean Eddy

Associate Research Scientist

University of Michigan