11:00 AM Pioneering Predictive Biomarkers & Surrogate Endpoints in Rare & Genetic Kidney Disease for Streamlined Translational Development
Time: 11:00 am
day: Pre-Conference Workshop Day
Details:
Join this workshop to gain critical knowledge and practical strategies for leveraging predictive biomarkers and surrogate endpoints to significantly streamline the translational development pathway for therapies in rare and genetic kidney diseases, ultimately benefiting patients by accelerating the availability of new treatments.
- Defining appropriate early and reliable biomarkers to predict disease progression and response to therapies to design efficient clinical trials
- Discussing novel endpoints for renal disease trials to reduce follow-up periods, cost, and complexity in clinical trials
- Defining appropriate surrogate endpoints for clinical trials in rare and common kidney diseases
- Identifying and validating surrogate endpoints that correlate with long-term outcomes in rare diseases that lack natural history data
- Developing companion diagnostics alongside new drugs to reliably identify the specific genetic mutations or biomarkers that predict a patient’s response to a drug
- Using patient registries and designing innovative clinical trials with novel endpoints that could translate findings from the rare disease space to the broader chronic kidney disease population
