Matthias Kretzler

Company: University of Michigan

Job title: Professor of Internal Medicine & Bioinformatics

Seminars:

Panel Discussion: Streamlining or Impeding Clinical Success? Defining the Balance Between Precision Medicine & Patient Exclusion 12:00 pm

How far should we be selecting patients that are fast progressors to streamline understanding of efficacy? Segmenting patients in rare kidney diseases: how homogeneous does the patient population need to be in a small patient population? Considering impact of precision medicine on commercial viability of drugs and ethical implications of excluding patients from trialsRead more

day: Day Two

Navigating Enrichment of Clinical Study Populations to Establish Drug Efficacy in a Precision Medicine Era 9:00 am

Implementing prognostic enrichment design to execute trials with fast progressors Enrolling clinical trial populations based on biomarker profiles to facilitate clinical trial efficiency Reducing heterogeneity with less restrictive entry criteria to monitor safety and efficacyRead more

day: Day One